Integrated Clinical-Genetic-Pathological Analysis Expands the Phenotypic and Molecular Spectrum of PPNAD Across Carney Complex and Isolated Forms.
2026-08-03, European Journal of Endocrinology (10.1093/ejendo/lvag137) (online)Maria Candida B V Fragoso, Madson Q Almeida, Jérôme Bertherat, Victor Srougi, Aliny Weber Kuhn, Antonio Marcondes Lerario, Helaine Laiz Charchar, Beatriz Marinho de Paula Mariani, Patricia Vaduva, Mirian Yumie Nishi, Felipe Lourenco Ledesma, José Luis Chambô, Berenice B Mendonca, and Ana Claudia Latronico (?)
Primary pigmented nodular adrenocortical disease (PPNAD) is a rare cause of ACTH-independent Cushing syndrome (CS), occurring in isolation or as part of Carney complex (CNC); its phenotypic and molecular spectra remain incompletely defined.
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