An increase in gastrointestinal infections in Early Childhood Education and Care notified to the public health unit in the Metro South area of Brisbane, Australia, coincided with the peak of the first Omicron wave in 2022. This made public health messaging and advice on outbreak management challenging. We hypothesised that gastrointestinal symptoms were a feature of the Omicron variant infection. At the time, there was a paucity of data on presenting symptoms of coronavirus disease 2019 (COVID-19) by the Omicron variant of SARS-CoV-2 among Australian children.